Parenteral nutrition (PN) is lifesaving for patients with short bowel syndrome and other gastrointestinal disorders, however long-term use may lead to complications including hepatosteatosis and ...

Crown BioScience experts explore how 3D in vitro assays mimic the suppressive tumor microenvironment to improve drug response ...

Combining a serum-free medium with a xeno-free serum replacement creates a reliable system for generating functional dendritic cells and macrophages. Myeloid cells such as dendritic cells and ...

Nature 545: 495-499. 47. Liu N, Zhang J, Yin M, et al. (2021): Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization.

This study sought to determine whether the SOCS3/JAK/STAT3 signaling pathway, which controls macrophage polarization, contributes to the cardiotoxicity caused by PD-1/PD-L1 inhibitors. The PD-1/PD-L1 ...

The new material combines the functions of hydrogen's antioxidant and anti-inflammatory properties and magnesium's promotion of angiogenesis and macrophage polarization, among others. They work ...

The new material combines the functions of hydrogen's antioxidant and anti-inflammatory properties and magnesium's promotion ...

The study involved a comprehensive dataset constructed from 35 carefully selected academic papers, out of an initial 128, focusing on 13 features related to macrophage polarization. After ...

Background Injured or reactive biliary epithelial cells participate in most chronic liver injuries in a process referred to as ductular reaction, which involves multicellular interactions with marked ...

In the article by Zhang et al, “Targeting NPM1 Epigenetically Promotes Postinfarction Cardiac Repair by Reprogramming Reparative Macrophage Metabolism,” which published online on February 23, 2024, ...

Schematic representation depicts the mechanism by which the ENO2-derived oncometabolite PEP directly binds to HDAC1 and thereby promotes H3K18la, which promotes macrophage polarization and leads ...