Safes can be found around the estate in Blue Prince, either out in the open or hidden to the eye, but you’ll need a safe code ...

so they figure out the safe room's secret code while Jimmy's catching some Z's. They go in and shoot him. Jimmy, however, is a tough kid. He survives, gets them back, and locks them in the vault ...

Safe codes and combinations for The Last of Us 2 allow you to access weaponry enhancements, ammunition, and incentives like the Big Win gun store.