In a recent interview with Entertainment Weekly, Bruckheimer revealed that he has spoken to Depp about coming back for the sixth Pirates film, and the actor is at least open to the idea. The famous Producer explained: If he likes the way the part's written,

Johnny Depp may don the dodgy braids and bandana one more time to star as Jack Sparrow in another Pirates of the Caribbean movie. In an interview with Entertainment Weekly, film-producing legend Jerry Bruckheimer said he has talked to Depp, and is persuaded the actor would be game to return, if the script is right.

One interesting thing about Bruckheimer's interest in bringing Depp back is that he's confirmed "Pirates of the Caribbean 6" will reboot the franchise.