The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta …

Apr 1, 2023 · In this paper, we will discuss the structures of IL-2 and IL-2R, the biological function of CD25 and its important role in tumor therapy. In addition, the latest research on drugs targeting …

CD25 CD25, also known as the α-subunit of the IL-2 receptor, is involved in the regulation of T cell function. Similar to mice with impaired FOXP3, IL-2Rα deficient mice exhibit lethal …

Jul 21, 2025 · The CD25 marker is a protein with a dual function in immune activation and suppression, a balance that is fundamental to both health and medical intervention.

Elevated levels of soluble IL-2Ra/CD25 may also have clinical and prognostic significance in patients with various lymphomas.

Oct 3, 2024 · CD25, also known as IL-2Rα, is highly expressed on Tregs and plays a vital role in their survival and function. CD25 forms part of the high-affinity receptor for IL-2, a cytokine essential for …

, Webb JR, Nelson BH. CD25 identifies a subset of CD4+FoxP3- TIL that are exhausted yet prognostically favorable in human ovarian cancer. Cancer Immunol Res. 2015;3(3):245-253. …

Explore how CD25 antibodies precisely target immune cells, revealing their intricate mechanisms and diverse applications in modern medicine.

CD25, or Soluble Interleukin 2 Receptor, is an integral part of your immune system, facilitating communication between immune cells and coordinating the body's defense against illness and …

CD25, expressed and secreted by such DC may capture IL-2 and thereby suppress T-cell proliferation, by this means providing an accessory mechanism of DC-mediated immune suppression. We also …