Trigeminal Neuralgia Clinical Manifestations. Trigeminal neuralgia, also called Fothergill disease, tic douloureux, trifacial neuralgia, is a long-term pain disorder that affects the trigeminal nerve, the nerve responsible for sensation in the face and motor functions such as biting and chewing. It is a form of neuropathic pain. | Dr. Najeeb

42K views · 812 reactions | Trigeminal neuralgia is primarily caused by nerve compression, often by a blood vessel, leading to demyelination of the trigeminal nerve and subsequent hyperexcitability. This compression, particularly at the trigeminal root entry zone in the brainstem, disrupts normal nerve function, resulting in sharp, electric shock-like pain. | Dr. Najeeb | Facebook